This landmark study from SPINE pitted manipulation against NSAID's and placebo. The results of this study are thorough, powerful, and clear. This is one of my favorite studies related to spinal manipulation (adjustments).
“This is the first time that spinal manipulation was investigated in a double-blinded randomized controlled design showing clear superiority compared with placebo and NSAID.”
“HVLA manipulation can be recommended for the therapy for acute nonspecific LBP.”
“Final evaluation showed manipulation being significantly better than NSAID and clinically superior to placebo.”
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